hrp0086lbp9 | (1) | ESPE2016

Osteoprotegerin and Insulin Resistance in Childhood Obesity: A New Interplay?

Kotanidou Eleni , Kyrgios Ioannis , Karalazou Paraskevi , Maggana Ioanna , Tzimagiorgis Georgios , Galli-Tsinopoulou Assimina

Background: A positive association between osteoprotegerin (OPG) levels and cardiovascular morbidity and mortality has been recently reported. Additionally, there is evidence that OPG in obese adults participates in the pathogenesis of atherosclerosis and cardiovascular diseases by promoting inflammation, which is known to be linked to insulin resistance (IR). There is few data regarding the relationship among obesity-IR-OPG, in youth.Objective and hypot...